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Regeneration cell therapy for brain hemorrhagic strokes

Description

Implant of autologous bone marrow stromal cells from the patient, for the treatment of after-effects in brain hemorrhagic stroke.

Indications

Neovascularization through the treatment with marrow stem cells in brains that have suffered a brain stroke.

Product

Autologous bone marrow stromal cell suspension.

Preclinical Trials

An experimental model to brain hemorrhagic injury in adult Wistar rats was developed for a subsequent treatment with heterologous cell therapy.

The preclinical study was finished by the end of 2011 with excellent results that confirmed our main hypothesis.

Publications

  • Vaquero J. et al. (2006). “Cell therapy using bone marrow stromal cells in chronic paraplegic rats: systemic or local administration”. Neurosci Lett; 398 (1-2): 129-34.
  • Otero L. et al. (2011). “Allogeneic bone marrow stromal cell transplantation after cerebral hemorrhage achieves cell transdifferentiation and modulates
    endogenous neurogenesis”. Cytotherapy, July 2011.

Intellectual Property

  • Spanish Patent GRANTED (date of concession 30-Jan-2012)
  • European Patent pending: Priority date 20th November 2011
  • The application is pending in: USA, Australia, Canada, Brazil, China, India, Russia and Japan.

 

 

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